Tephestrol Substance - Fito-drug of estrogen

"  FESTROL® Tephestrol® Fito-drug of estrogen Active ingredient: Sum of complex terpenoid esters with aromatic alcohols and acids ferutinine and tenuferidine isolated from wild plant Ferula tenuisecta ( ferule finely) . Pharmacological properties: Tefestrol® shows high estrogenic activity at all levels of the hypothalamic-pituitary-ovarian system. When injected into the body stimulates the proliferation of the mucous membrane of the vagina, uterus and endometrium secondary female sexual characteristics in their underdevelopment, eliminates the common disorders that occur due to lack of gonadal function. The drug activates the processes of synthesis and secretion of FSH and luteinizing hormone in the pituitary gland and stimulates ovulation. Tefestrol ® has no effect on blood pressure and breathing, has no carcinogenic, teratogenic and cumulative, does not alter the secretion of endogenous estrogen. At therapeutic doses, does not have embryotoxic. Indications: Tefestrol® is used in the delay of sexual development, menstrual irregularities, dysfunctional uterine bleeding, menopause. The drug improves the general condition of women in menopause, in combination with progestogens effective as hormone replacement therapy. Tefestrol® is effective for the treatment of patients with ovarian failure: the lack of development of secondary sexual characteristics, primary and secondary amenorrhea, hypoplasia of the reproductive system, hypomenstrual syndrome, as well as miscarriage, infertility, endocrine origin, preparation for childbirth, the pathological course of delivery. Low toxicity and mild Tefestrol® therapeutic effects allow you to apply it for a long time, in combination with gestagens as a replacement therapy for many gynecological diseases. Advantages: Tefestrol® is not inferior to the activity with synthetic estrogenic drug ethinylestradiol ( mikrofollinu) , and estrofenu sinestrola. Compared with Tefestrol® is less toxic, does not cause allergy, operating more smoothly in the target organs, does not cause changes in the hemostatic system is safe for use in pediatric gynecology and treatment of pregnant women, well-tolerated. Dosage: Assign inside, regardless of the meal. Dose and duration of use should be individualized depending on the nature of the disease and treatment. The therapeutic dose of 0, 005g. The highest single dose - 0.02, the highest daily dose - 0.05 g Side effects: During the pilot studies and extensive clinical use Tefestrol® side effects and complications. Contraindications: Tefestrol® should not be used for malignant and benign tumors of the genital organs, breasts and other Oran, as well as hormone-dependent diseases of the genital organs ( uterine fibroids, endometriosis) .